
This post carries a warning: watch what you say. You never know who may be listening, much less recording. And, if you’re a college professor, you might as well assume the latter at all times. This is a verbatim transcript of a section of a Biochemistry course in which an instructor, perhaps unwisely, decided to expound on what may cause the difference between a person being a “sad” drunk versus a “happy” drunk and manages to divulge some interesting personal details, a recipe for “Hopping Gators”, and thoughts on spousal shootings in the process.
Is there Biochemistry involved? Yes. Is it the most appropriate topic, or approach, in a college classroom? Well, you decide.
I think one of the more interesting things is why you get happy drunks and sad drunks. Right? You guys read this chapter? I should give you a quiz so you’ll read it.
If you’re exercising a lot, real strenuously, you sort of wear out your glycogen reserves and you sort of get in a hungry stage, and if you go out drinking with your buddies, right, you get a bigger bang for your buck . Right? And depending on how well fed you [are or] not, you can, you can, get sort of, as we say here, uh, agitated? Impaired judgment? Shall we say? And why does that happen?
Well it happens because when you drink, you have to uh, remove the alcohol, and you remove the alcohol by alcohol dehydrogenase and acid aldehyde dehydrogenase. This creates higher levels of NADH in the cytosol. And so you’re not really getting a lot on energy, per say, at that point in time. And then those higher levels of NADH cause a shift of pyruvate to lactate, and it also causes oxaloacetate to malate shift. These are the precursors of glucose from the liver.
So, you know, if you’re exercising, and you go drinking, you get, you get a little, little wilder, you know. Have you ever tried Gatorade and beer? Hopping gators? Get drunk on that? It used to be popular when I was in college. Well, well, Gatorade and anything , because the the the carbonate and the glucose gives you [I couldn't really hear this part, something about the carbonate and the glucose and an enhanced uptake, and screwing something.]
Anyway, so, so you end up, uh, um, screwing up your glucose levels and just like any war usually starts when people are hungry . Or fights start when people are hungry . Or if you look at the Saturday night shootings of spouses, you know, it all happens after alcohol . So, vitamin B’s play a role in this. I’m going to ask you some roles for thiamine and, and uh, pyridoxine and some of this stuff. You know, beer has a lot of B vitamins, but, but typically if you’re drinking a light American beer in, into excess, you’ll go into a vitamin B deficiency.
So. If you want to be happy and drunk, you should drink and eat, like Europeans do and have lots of B vitamins. And don’t drink – don’t go out, like, at midnight and and drink like a fish, and not expect to have the consequences .
So, to make sure we understand the drinking rules according to Professor Bombast, the promised quiz:

Loading ...

Loading ...

Loading ...

Loading ...

Loading ...

Loading ...
* Please note that my views on alcohol consumption are in no way linked to the professor quoted above and that I believe moderation, safety of one’s self, and the safety of others are always of primary importance and that this is not meant to glorify or encourage overconsumption in any way. I’m not sure how you might get that impression, but someone surely will, so, if that’s you, go back and re-read this several times until it sticks.